产品货号：
Z14133
中文名称：
Cytokeratin 6抗体
英文名称：
Anti-Cytokeratin 6 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Cytokeratin 6 Antibody |
| 指标别名 | CK6A;CK6B;CK6C;CK6D;CK6E;Keratin Type II Cytoskeletal 6A;Keratin Type II Cytoskeletal 6B;Keratin Type II Cytoskeletal 6C;Keratin Type II Cytoskeletal 6D;Keratin Type II Cytoskeletal 6E;KRT6;KRT6A;KRT6B;KRT6C;KRT6D;KRT6E |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,ICC,IF,IHC |
| 基因名称 | KRT6A/KRT6B/KRT6C |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | recombinant protein |
| 计算分子量 | 60kDa |
| 成分 | Rabbit IgG,1mg/mL in PBS with 0.02% sodium azide,50% glycerol,pH7.2 |
| 纯化方式 | ProA affinity purified |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue,where they constitute up to 85% of mature keratinocytes in the vertebrate epidermis.Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells.The alpha-helical coiled-coil dimers associate laterally end-to-end to form 10nm diameter filaments.Cytokeratins,which are useful markers of tissue differentiation,also aid in the characterization of malignant tumors.IL-1 and TNF汐induce transcription of cytokeratin 6 in epidermal keratinocytes via the C/EBP汕transcription factor.In humans,multiple isoforms of cytokeratin 6 (6A-6F),encoded by several highly homologous genes,have distinct tissue expression patterns,and cytokeratin 6A is the dominant form in epithelial tissue.The gene encoding human cytokeratin 6A maps to chromosome 12q13,and mutations in this gene are linked to several inheritable hair and skin pathologies. |
| Uniprot ID | P02538/P04259/P48668 |
| 基因名全称 | Keratin,type II cytoskeletal 6A |
| 蛋白名全称 | Keratin,type II cytoskeletal 6A |
| 推荐稀释比 | WB:1:1,000-1:2,000 ICC:1:100～1:500 IHC:1:50～1:200 |
相关搜索：Cytokeratin 6抗体，Cytokeratin 6多抗，Anti-Cytokeratin 6 Antibody